Phase I/II Study of Vaccination With Antigen Loaded Dendritic Cells (DCs) in Hormone-Refractory Prostate Cancer
NCT01897207 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2015-08-17
Summary
The main aim of this trial is to assess the response rate, the feasibility and toxicity of the treatment with antigen loaded Dendritic Cell Vaccination in Prostate Cancer patients. Furthermore we want to investigate biological responses by measuring markers of in-vivo and ex-vivo immunomodulation.
Conditions
- Cancer of the Prostate
Interventions
- BIOLOGICAL
-
Dendritic cell application
S.C. injection of peptide pulsed autologous dendritic cells
Sponsors & Collaborators
-
Cantonal Hospital of St. Gallen
lead OTHER
Principal Investigators
-
Thomas Cerny, Prof. Dr. · Department of Medical Oncology, Cantonal Hospital St. Gallen, Switzerland
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-11-30
- Primary Completion
- 2009-08-31
- Completion
- 2011-10-31
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