Laparoscopic Versus Open Lower Mediastinal Lymphadenectomy for Esophagogastric Junction Cancer

Summary

Mediastinal lymph node dissection has been adopted as standard treatment for adenocarcinoma of esophagogastric junction(AEJ). This multi-center, exploratory, prospective, cohort study aims at provide standard technical details of laparoscopic mediastinal lymph node dissection, and explore the potential clinical effects, gather key information for following study regarding sample size calculation, primary outcome and feasibility.

Conditions

• Gastric Cancer

Interventions

PROCEDURE

Radical gastrectomy with dissection of lower mediastinal lymph node

Radical gastrectomy for gastric cancer should be consistent with Japanese gastric cancer treatment guideline.

Sponsors & Collaborators

• Peking University Cancer Hospital & Institute

  collaborator OTHER

• Changzhi People's Hospital

  collaborator OTHER

• The First Affiliated Hospital of Dalian Medical University

  collaborator OTHER

• Fujian Medical University Union Hospital

  collaborator OTHER

• Shanghai Zhongshan Hospital

  collaborator OTHER

• Fudan University

  collaborator OTHER

• Guangdong Provincial People's Hospital

  collaborator OTHER

• Guangdong Provincial Hospital of Traditional Chinese Medicine

  collaborator OTHER

• Hebei Medical University Fourth Hospital

  collaborator OTHER

• Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

  collaborator OTHER

• The First Hospital of Jilin University

  collaborator OTHER

• The First Affiliated Hospital with Nanjing Medical University

  collaborator OTHER

• The First Affiliated Hospital of Air Force Medicial University

  collaborator OTHER

• Nanfang Hospital, Southern Medical University

  collaborator OTHER

• The Affiliated Hospital of Qingdao University

  collaborator OTHER

• Affiliated Hospital of Qinghai University

  collaborator OTHER

• The First Affiliated Hospital of Xiamen University

  collaborator OTHER

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• Shanxi Province Cancer Hospital

  collaborator OTHER

• RenJi Hospital

  collaborator OTHER

• Ruijin Hospital

  collaborator OTHER

• Beijing Friendship Hospital

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Tianjin Medical University Cancer Institute and Hospital

  collaborator OTHER

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• Zhejiang Cancer Hospital

  collaborator OTHER

• Chinese PLA General Hospital

  collaborator OTHER

• First Hospital of China Medical University

  collaborator OTHER

• Cancer Institute and Hospital, Chinese Academy of Medical Sciences

  collaborator OTHER

• Sun Yat-sen University

  collaborator OTHER

• Peking University

  lead OTHER

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-08-01

Primary Completion

2023-07-01

Completion

2026-07-01

Countries

• China

Study Locations