Monitoring Efficacy of Radiotherapy in Lung Cancer and Esophageal Cancer
NCT04014465 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2021-02-02
Summary
Lung cancer, one of the malignant tumors which poses a threat to human's health, has increased morbidity and mortality recently. Radiotherapy, as one of the common treatments, has important value in clinical application. Esophageal cancer, one of the most common digestive system cancers, has poor prognosis and high mortality. Esophageal cancer has high aggressive and many patients can't get surgical treatment because of the tumor metastasis at the time of diagnosis.Currently, chemoradiotherapy has become one of the standard treatment regimens for patients with unresectable esophageal cancer in National Comprehensive Cancer Network(NCCN). So radiotherapy is one of the most important treatments in esophageal cancer.
Currently, the efficacy evaluation method of radiotherapy is by imaging examination after several courses of treatment. However, new reports suggest that circulating tumor DNA(ctDNA) has the potential to be an indicator of therapeutic effectiveness and recurrence risk.
Conditions
- Lung Cancer
- Esophageal Cancer
Sponsors & Collaborators
-
Chinese Academy of Medical Sciences
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-02-01
- Primary Completion
- 2022-06-30
- Completion
- 2022-12-01
Countries
- China
Study Locations
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