Hypomagnesemia Associated With Proton-Pump Inhibitor Use
NCT04426994 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 211672
Last updated 2020-06-11
Summary
Use of proton pump inhibitors has been associated with hypomagnesemia. However, various case-control or prospective studies have found conflicting results with regards to proton pump inhibitors use and development of hypomagnesemia. Our aim was to evaluate the likelihood that proton pump inhibitors contributed to severe hypomagnesemia in a retrospective cohort of patients admitted with severe hypomagenesemia. We also aimed to look for risk factors leading to development of hypomagnesemia amongst users of proton pump inhibitors
Conditions
- Proton Pump Inhibitor Adverse Reaction
- Hypomagnesemia
- Arrhythmias, Cardiac
- Seizures
- Hypocalcemia
- Hypokalemia
Interventions
- DRUG
-
proton pump inhibitor use
Patients using long term proton pump inhibitor
Sponsors & Collaborators
-
Changi General Hospital
lead OTHER
Principal Investigators
-
Troy H Puar, MRCP · Changi General Hospital
Eligibility
- Min Age
- 14 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-31
- Primary Completion
- 2018-01-30
- Completion
- 2019-09-30
- FDA Drug
- Yes
Countries
- Singapore
Study Locations
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