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Prevalence and Intervention of Hypomagnesemia in Users of Proton-pump Inhibitors

NCT02518659 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2015-08-10

No results posted yet for this study

Summary

Hypomagnesemia is a severe side effect of longterm use of all available proton-pump inhibitors (PPIH). It develops due to intestinal malabsorption of Mg2+.

This study investigates the application of dietary inulin fibers in users of proton-pump inhibitors with such a hypomagnesemia. To this end, repetitive short-term trials of 14 days of orally administered inulin, separated by a wash-out period of 14 days each were performed in cases of PPIH and controls. This study was not blinded or randomized.

Conditions

  • Hypomagnesemia, Intestinal, With Secondary Hypocalcemia
  • Drug Induced Hypomagnesemia

Interventions

DIETARY_SUPPLEMENT

Inulin

This is the Intervention

Sponsors & Collaborators

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • René Bindels, Professor · Radboud University Medical Center

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2015-02-28
Completion
2015-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02518659 on ClinicalTrials.gov