MedTrace Logo

COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss

NCT04395144 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2021-03-23

No results posted yet for this study

Summary

Prone positioning is an established intervention in mechanically ventilated acute respiratory distress syndrome (ARDS) patients, with demonstrated reductions in mortality.

Preliminary data suggest that awake proning in patients with COVID-19 treated with high-flow nasal oxygenation (HFNO) improves gas exchanges, and might be associated with a reduced need of mechanical ventilation, and reduced mortality. Further investigation in a formal randomized-controlled trial is need.

Conditions

  • Coronavirus Infection
  • COVID
  • Severe Acute Respiratory Syndrome
  • Respiratory Failure
  • Respiratory Insufficiency
  • Respiratory Distress Syndrome
  • ARDS
  • Lung Diseases

Interventions

PROCEDURE

Awake Prone Positioning

Patients will receive instruction to remain in prone position as long and as often as possible, up to 16h/24h

PROCEDURE

Standard care

Patients will not receive any special instructions with regards to proning.

Sponsors & Collaborators

  • Hôpital de Verdun

    lead OTHER

Principal Investigators

  • Ivan Pavlov, MD · Hôpital de Verdun

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-05-15
Primary Completion
2021-03-15
Completion
2021-03-15

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04395144 on ClinicalTrials.gov