MedTrace Logo

Neo-adjuvant Short Course Chemo-radiation Therapy in Locally Advanced Rectal Cancer Patients

NCT04370418 · Status: UNKNOWN · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 8

Last updated 2022-02-28

No results posted yet for this study

Summary

* The primary objective of this trial is to assess the safety and feasibility of 5-FU when given concurrently with5 Gy x 5 fractions IMRT.
* The secondary endpoint is to assess disease local control and the response rate after short course radiotherapy concurrent with dose escalation infusion 5-fu followed by mFOLFOX and delayed surgery.

Conditions

  • Neo-adjuvant Short Course Chemo-radiotherapy in Locally Advanced Cancer Rectum

Interventions

DRUG

short course chemo-radiation with 5-fluorouracil

neo-adjuvant short course chemo-radiation in locally advanced rectal cancer patients followed by delayed surgery

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • taha z mohran, professor · Assiut University

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-05-01
Primary Completion
2021-06-01
Completion
2023-09-30

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04370418 on ClinicalTrials.gov