Effects of Serotonin Agonist Citalopram on Multimodal Esophageal Stimulation in Healthy Volunteers
NCT04355455 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2020-04-21
Summary
To investigate the effect of citalopram, a selective serotonin reuptake inhibitor, on esophageal sensitivity.
Conditions
- Gastroesophageal Reflux
Interventions
- DRUG
-
Citalopram
40 mg citalopram intravenously
- DRUG
-
Saline solution
Sponsors & Collaborators
-
Universitaire Ziekenhuizen KU Leuven
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-07-31
- Primary Completion
- 2011-12-31
- Completion
- 2012-01-31
More Related Trials
-
The Effect of SSRIs on Threat of Shock Potentiated Neural Circuitry
NCT07074652 ·Status: COMPLETED ·Phase: NA
-
Pharmacokinetics of Citalopram in Patients With Short Bowel Syndrome
NCT00876226 ·Status: WITHDRAWN ·Phase: NA
-
Mood Effects of Serotonin Agonists
NCT03790358 ·Status: COMPLETED ·Phase: PHASE1
-
Beta-CIT-SPECT and Neurophysiology in Depression
NCT00145132 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacodynamics and Pharmacokinetics of Citalopram and Escitalopram
NCT00613470 ·Status: COMPLETED ·Phase: PHASE1
-
Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety
NCT02818751 ·Status: COMPLETED ·Phase: NA
-
The Effects of Increased Central Serotonergic Activity on Information Processing
NCT00206934 ·Status: COMPLETED ·Phase: NA
-
Escitalopram in Depressive Patients With Acute Coronary Artery Syndrome
NCT00419471 ·Status: COMPLETED ·Phase: PHASE4
-
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
NCT05685407 ·Status: COMPLETED ·Phase: PHASE1
-
PF-04995274 and Emotional Processing in Un-medicated Depression
NCT03516604 ·Status: COMPLETED ·Phase: PHASE1
-
Treatment of Depression in the Elderly
NCT00130455 ·Status: TERMINATED ·Phase: PHASE4
-
Outcome Following Antidepressant Treatment on Possible Endo-Phenotypes for Major Depression
NCT00386841 ·Status: COMPLETED ·Phase: PHASE4
-
Neural Responses and Dysphoria: Modulation by a Pharmacological Probe
NCT01101685 ·Status: COMPLETED ·Phase: PHASE4
-
A Safety and Tolerability Single Ascending Dose Study in Healthy Volunteers
NCT00583544 ·Status: COMPLETED ·Phase: PHASE1
-
Gustatory Modulators Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy
NCT04923425 ·Status: COMPLETED
-
Efficacy and Safety of Escitalopram Doses up to 50mg in Treatment of MDD
NCT00785434 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Impact of Escitalopram on Quality of Life and Social Functionality in Patients With Major Depressive Disorder With Anxiety Symptom
NCT01870843 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Antidepressant Efficacy of a Selective, High Affinity Enkephalinergic Agonist in Anxious Major Depressive Disorder (AMDD)
NCT00759395 ·Status: COMPLETED ·Phase: PHASE2
-
The Effects of Escitalopram on Cytokines
NCT01587326 ·Status: UNKNOWN ·Phase: NA
-
Brain Effects of Escitalopram and Citalopram Using fMRI
NCT00825825 ·Status: COMPLETED ·Phase: PHASE4
-
Escitalopram for Agitation in Alzheimer's Disease
NCT03108846 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
7-day Simvastatin and Emotional Processing
NCT04652089 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Ethnic Variations in Antidepressant Response
NCT00047671 ·Status: COMPLETED ·Phase: PHASE4
-
NMDA Modulation in Antidepressant Nonresponders With Major Depressive Disorder
NCT05136755 ·Status: RECRUITING ·Phase: PHASE2
-
Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients
NCT01352572 ·Status: UNKNOWN ·Phase: NA