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THRIVE Use in Pediatric Populations- Multi Site

NCT04322994 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 175

Last updated 2025-03-27

Study results available
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Summary

THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia. The use of high-flow nasal cannula oxygen supplementation during anesthesia for surgical procedures has been a recent development in the adult population, with limited data analyzing the pediatric population. This study will determine whether high flow nasal cannula oxygen supplementation during surgical or endoscopic procedures can prevent desaturation events in children under anesthesia and improve the outcomes of that surgery.

Conditions

  • Oxygen Deficiency
  • Desaturation of Blood
  • Hypoventilation
  • Anesthesia; Adverse Effect

Interventions

DEVICE

Transnasal Humidified Rapid-Insufflation Ventilatory Echange

The use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia.

Sponsors & Collaborators

  • Nationwide Children's Hospital

    collaborator OTHER

  • Ann & Robert H Lurie Children's Hospital of Chicago

    collaborator OTHER

  • Boston Children's Hospital

    collaborator OTHER

  • UC Davis Children's Hospital

    collaborator UNKNOWN

  • Stanford University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-10-21
Primary Completion
2024-01-19
Completion
2024-01-19
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04322994 on ClinicalTrials.gov