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Identifying Novel Variants in the DPYD Gene in Patients of Non-Western Descent

NCT04300361 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 600

Last updated 2020-03-09

No results posted yet for this study

Summary

This is a observational, multicenter study to identify novel variants of the DPYD gene which are possible deleterious in patients of non-Western descent.

Conditions

  • Neoplasms

Interventions

GENETIC

Sequencing of DPYD gene

The DPYD gene of non-Western patients will be sequenced to identify DPYD variants that are possibly associated with an increased risk of developing severe fluoropyrimidine-related toxicity.

Sponsors & Collaborators

  • The Netherlands Cancer Institute

    collaborator OTHER

  • Erasmus Medical Center

    collaborator OTHER

  • Haga Hospital

    collaborator OTHER

  • Medical Center Haaglanden

    collaborator OTHER

  • Leiden University Medical Center

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-01
Primary Completion
2022-03-01
Completion
2022-08-01
FDA Drug
Yes

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04300361 on ClinicalTrials.gov