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Mauriac Syndrome: Isotopic Techniques and Genetic Analysis

NCT04275141 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6

Last updated 2024-05-08

No results posted yet for this study

Summary

Mauriac syndrome (MS) is an entity of individuals combining poorly controlled diabetes mellitus type 1, short stature and glycogenic hepatopathy. Thus, the functional significance of Mauriac syndrome for glucose metabolism remains disputed, and whether genetic defects in glycogen metabolism contribute to glycogenic hepatopathy in MS remains to be clarified.Coupling the genetic analysis of targeted genes involved in glucose regulation with a dynamic exploration will eventually determine if a genetic abnormality leads to the disease and explains the nature of the phenotype.

Conditions

Interventions

OTHER

oral glucose load

oral glucose load (60g) followed by exercise at fixed wattage (60W) for 30 min

OTHER

exercise test

oral glucose load (60g) followed by exercise at fixed wattage (60W) for 30 min

Sponsors & Collaborators

  • University Hospital, Geneva

    collaborator OTHER

  • University of Lausanne

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-17
Primary Completion
2022-07-31
Completion
2023-12-30

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04275141 on ClinicalTrials.gov