A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers
NCT04260802 · Status: TERMINATED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 73
Last updated 2026-01-12
Summary
This study will investigate OC-001 as monotherapy, and in combination with, Avelumab, in various cancer types
Conditions
- Cancer
- Neoplasms
- Metastatic Cancer
- Triple Negative Breast Cancer
- Gastric Cancer
- Cervical Cancer
- Ovarian Cancer
- Hepatocellular Carcinoma
- Squamous Cell Carcinoma of Head and Neck
- Urothelial Carcinoma
- Urothelial Neoplasm
- Non Small Cell Lung Cancer
- Renal Cell Carcinoma
- Locally Advanced Solid Tumor
- Locally Advanced Malignant Neoplasm
- Squamous Cell Carcinoma
- Sarcoma
- Merkel Cell Carcinoma
- Bladder Cancer
Interventions
- DRUG
-
OC-001
Administered IV.
- DRUG
-
Drug: OC-001 in Combination with Avelumab
Administered IV.
Sponsors & Collaborators
-
Ocellaris Pharma, Inc.
lead INDUSTRY
Principal Investigators
-
Ocellaris Pharma, Inc · Ocellaris Pharma, Inc.
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-09-24
- Primary Completion
- 2025-11-07
- Completion
- 2025-11-07
Countries
- Canada
Study Locations
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