MedTrace Logo

Impact of Interval Training on Sympathetic Hyperactivity and Vascular Function

NCT04248894 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35

Last updated 2026-04-29

No results posted yet for this study

Summary

In this study, the investigators are testing the hypothesis that reduction in sympathetic activity would be greater following high-intensity interval training (HIIT) than moderate-intensity continuous training (MICT) and correspond with improvements in peripheral vascular function, and skeletal muscle function in patients with heart failure with reduced ejection fraction (HFrEF).

Conditions

Interventions

OTHER

Exercise training of High Intensity

High intensity

OTHER

Exercise training of Moderate Intensity

Moderate intensity

OTHER

Untraining

Sedentary

Sponsors & Collaborators

  • University of Sao Paulo General Hospital

    lead OTHER

Principal Investigators

  • Calors Negrao, PhD · aHeart Institute, University of São Paulo Medical School, São Paulo, Brazil

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2021-04-30
Completion
2023-12-31

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04248894 on ClinicalTrials.gov