The SMARTEX Heart Failure Study

Summary

This protocol describes a randomized multicenter clinical trial designed to test the hypothesis that a 12-week program of high-intensity interval training (HIIT) yields larger beneficial effects in stable heart failure patients than current practice, defined as either a similar training program with the same volume of moderate continuous training (MCT) or a recommendation of regular exercise at moderate intensity at individual choice (RRE).

Conditions

• Heart Failure

Interventions

BEHAVIORAL

Moderate continuous training

3 weekly sessions of moderate continuous training for 12 weeks

BEHAVIORAL

Recommendation of regular moderate exercise

Recommendation of regular exercise at moderate intensity at individual choice. In addition patients will meet for treadmill walking in order to motivate for post intervention testing

BEHAVIORAL

high-intensity interval training

3 weekly sessions of high-intensity interval training in 12 weeks

Sponsors & Collaborators

• University Hospital, Antwerp

  collaborator OTHER

• UMC Utrecht

  collaborator OTHER

• Technical University of Munich

  collaborator OTHER

• Heart Center Leipzig - University Hospital

  collaborator OTHER

• Bispebjerg Hospital

  collaborator OTHER

• St. Olavs Hospital

  collaborator OTHER

• Helse Stavanger HF

  collaborator OTHER_GOV

• Scientific Institute of Veruno

  collaborator UNKNOWN

• Centre Hospitalier du Luxembourg

  collaborator OTHER

• Alesund Hospital

  collaborator OTHER

• Helse Nord-Trøndelag HF

  collaborator OTHER

• Norwegian University of Science and Technology

  lead OTHER

Principal Investigators

• Øyvind Ellingsen, MD, PhD · National Taiwan Normal University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2009-01-31

Primary Completion

2013-09-30

Completion

2014-07-31

Countries

• Belgium
• Denmark
• Germany
• Italy
• Luxembourg
• Netherlands
• Norway

Study Locations