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tDCS Plus Physical Therapy for Progressive Supranuclear Palsy

NCT04237948 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2020-01-23

No results posted yet for this study

Summary

Objective of the study:

To test the efficacy of cerebellar transcranial direct current stimulation (tDCS) associated with physical rehabilitation on postural instability and falls in progressive supranuclear palsy using a double-blind design and wearing sensors technology

Design:

Twenty probable PSP patients with no dementia and still able to walk will be recruited for a randomized double-blind sham-controlled study. Each patient will be hospitalized for a four week physical rehabilitation. In the real-arm, the patients will undergo a ten cerebellar tDCS stimulations while the placebo arm will undergo sham stimulation.

Each patient will be evaluated before and after stimulation by PSP-rating scale (PSP-RS), cognitive tests and a battery of gait and movement tests using wearing sensors technology.

Conditions

Interventions

DEVICE

transcranial direct current stimulation (tDCS)

cerebellar tDCS consists in the application of a low intensity (1-2 mA) steady current through a surface scalp electrode over the cerebellum

BEHAVIORAL

Physical therapy

Hospitalized patients will undergo a 60 minutes physical treatment improving gait and postural instability for four weeks of time

Sponsors & Collaborators

  • Università degli Studi di Brescia

    collaborator OTHER

  • University of Kiel

    collaborator OTHER

  • Fondazione Europea di Ricerca Biomedica Ferb Onlus

    lead OTHER

Principal Investigators

  • Andrea Pilotto, MD · FERB onlus

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-01
Primary Completion
2019-11-15
Completion
2019-12-15

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04237948 on ClinicalTrials.gov