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Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized Patients

NCT04229511 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 520

Last updated 2020-01-18

No results posted yet for this study

Summary

DETERMINE trial is a prospective multicenter multinational cohort study. This study will be carried out to predict the risk of bloodstream infections (BSIs) or other types of invasive infection with carbapenem resistant K.pneumoniae in patients being colonized by CRKp. The results of DETERMINE trial would be quite important to prevent unnecessary coverage of carbapenem resistant Klebsiella pneumoniae in empirical treatment of colonized patients. In this study, both risk score model and decision tree algorithm will be constructed and compared with each other in terms of sensitivity, specificity, positive predictive value and negative predictive value.

Conditions

  • Bloodstream Infection
  • Pneumonia, Bacterial
  • Intra-abdominal Infection
  • Urinary Tract Infections
  • Osteomyelitis
  • Central Nervous System Infections
  • Acute Bacterial Skin and Skin Structure Infection

Interventions

DIAGNOSTIC_TEST

Detection of CRKp colonization

Detection of CRKp colonization will be performed in all participants by sceening with rectal swab

Sponsors & Collaborators

  • SCARE (Study group for carbapenem resistance)

    lead OTHER

Principal Investigators

  • Abdullah T Aslan, Dr. · Hacettepe University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-04-30
Primary Completion
2021-04-30
Completion
2021-11-30

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04229511 on ClinicalTrials.gov