MedTrace Logo

Oxygen Reserve Index to Reduce Hyperoxia

NCT04211246 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2022-03-31

No results posted yet for this study

Summary

Excessive oxygen administration is known to cause oxidative stress, and absorption atelectasis. Hyperoxia is very common in general anesthesia settings. Even though there are concerns in using excessive oxygen during general anesthesia, the optimal fraction of inspired oxygen (FiO2) for general anesthesia is not well studied.

The oxygen reserve index (ORI) is a parameter which can evaluate partial pressure of oxygen (PaO2) rating from 0 to 1. There are growing evidences in ORI that it might be helpful to reduce hyperoxia in critically ill patients in the intensive care unit, as well as in general anesthesia.

The aim of this study is to evaluate efficacy of oxygen reserve index to reduce hyperoxemia in major abdominal surgery.

Conditions

  • Hyperoxemia

Interventions

PROCEDURE

Titration of fraction of inspired oxygen (FiO2) guided by SpO2

Titration of fraction of inspired oxygen (FiO2) guided by SpO2

PROCEDURE

Titration of fraction of inspired oxygen (FiO2) guided by ORI and SpO2

Titration of fraction of inspired oxygen (FiO2) guided by ORI and SpO2

Sponsors & Collaborators

  • Eunah Cho, MD

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-07
Primary Completion
2022-03-28
Completion
2022-03-28

Countries

  • South Korea

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04211246 on ClinicalTrials.gov