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Safe Time for Apnea After Preoxygenation

NCT03239678 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2022-11-29

No results posted yet for this study

Summary

The use of 100% oxygen during the induction of general anesthesia is always preferable to have enough time to secure the airway by endotracheal intubation, because preoxygenation with a low oxygen concentration may reduce the safe time for apnea. However, using a low oxygen concentration during preoxygenation might prevent the formation of atelectasis. There is still no clear conclusion about the best oxygen concentration for preoxygenation. Our study is designed to evaluate the safety of preoxygenation with 80%, 60%, 40%, 30% and 21% oxygen by the safe time for apnea during the induction of general anesthesia.

Conditions

  • Anesthesia, General

Interventions

DRUG

100% Oxygen

Conventional preoxygenation with 100% oxygen

DRUG

30% Oxygen

preoxygenation with 30% oxygen

DRUG

21% Oxygen

preoxygenation with 21% oxygen

DRUG

40% Oxygen

preoxygenation with 40% oxygen

DRUG

60% Oxygen

preoxygenation with 60% oxygen

DRUG

80% Oxygen

preoxygenation with 80% oxygen

Sponsors & Collaborators

  • Sixth Affiliated Hospital, Sun Yat-sen University

    lead OTHER

Principal Investigators

  • Sanqing Jin, MD · Sixth Affiliated Hospital, Sun Yat-sen University

  • Zijia Li · Sixth Affiliated Hospital, Sun Yat-sen University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-08-01
Primary Completion
2017-12-30
Completion
2017-12-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03239678 on ClinicalTrials.gov