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Effects of Red Blood Cells Transfusion on Renal Blood Flow

NCT04194047 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 33

Last updated 2022-09-13

No results posted yet for this study

Summary

The renal Doppler resistive index (RRI) is a noninvasive tool that has been used to assess renal perfusion in the intensive care unit (ICU) setting. It is associated with the occurrence of acute kidney injury (AKI). Many parameters have been described as influential on the values of renal RI. Red blood cell (RBC) transfusion were shown to be able to increase renal oxygenation in animal model, whereas crystalloid resuscitation did not. We sought to describe the different effect of crystalloids infusion and RBC transfusion on renal blood flow, as evaluated with doppler ultrasound

Conditions

Interventions

OTHER

Transfusion

RBC transfusion (1 unit)

OTHER

Crystalloids infusion

Infusion of 500 ml of balanced crystalloids

Sponsors & Collaborators

  • Università degli Studi di Ferrara

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-01
Primary Completion
2022-09-01
Completion
2022-09-01

Countries

  • Italy

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04194047 on ClinicalTrials.gov