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Ventilation Heterogeneity Prior to Lung Resection

NCT04191174 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 115

Last updated 2024-01-05

No results posted yet for this study

Summary

This is a single centre prospective six-week observational study to understand the prevalence and clinical relevance of abnormal ventilation of the lung (assessed by Technegas ventilation single photon emission computed tomography (V SPECT) and hyperpolarized 129Xe magnetic resonance imaging (MRI)), in the presence or absence of airway inflammation (assessed by sputum cell counts), in lung cancer patients prior to lung resection surgery.

Conditions

Interventions

OTHER

Hyperpolarized 129Xe MRI

Hyperpolarized 129Xe MRI to evaluate ventilation heterogeneity

OTHER

Technegas V SPECT

Technegas V SPECT to evaluate ventilation heterogeneity

OTHER

Sputum Induction

Sputum induction to evaluate luminal cellular inflammation

Sponsors & Collaborators

  • Cyclomedica Australia Pty Ltd

    collaborator UNKNOWN

  • Ontario Lung Association

    collaborator OTHER

  • St. Joseph's Healthcare Hamilton

    collaborator OTHER

  • McMaster University

    lead OTHER

Principal Investigators

  • Parameswaran Nair, MD, PhD · McMaster University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-06
Primary Completion
2024-06-01
Completion
2024-12-01

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04191174 on ClinicalTrials.gov