MedTrace Logo

Close Assessment and Testing for Chronic Graft Versus Host Disease, CATCH Study

NCT04188912 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 267

Last updated 2025-10-02

No results posted yet for this study

Summary

This trial observes and collects samples from patients before and after stem cell transplantation to learn more about how and why a complication called chronic graft-versus-host disease (GVHD) develops after stem cell transplantation. Performing close observation and various types of testing may enable doctors to notice symptoms or problems sooner than they would normally have been noticed and predict which patients will develop chronic GVHD.

Conditions

  • Hematopoietic and Lymphoid Cell Neoplasm

Interventions

PROCEDURE

Biospecimen Collection

Undergo collection of blood, tears, saliva, buccal mucosa, feces, and tissue samples

PROCEDURE

Optical Coherence Tomography

Undergo optical coherence tomography

PROCEDURE

Spirometry

Undergo portable spirometry

OTHER

Survey Administration

Complete survey

OTHER

Digital Photography

Undergo digital photography

OTHER

Quality-of-Life Assessment

Ancillary studies

OTHER

Medical Chart Review

Review of medical charts

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • National Institutes of Health (NIH)

    collaborator NIH

  • Fred Hutchinson Cancer Center

    lead OTHER

Principal Investigators

  • Stephanie Lee · Fred Hutch/University of Washington Cancer Consortium

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-13
Primary Completion
2025-09-29
Completion
2025-09-29

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04188912 on ClinicalTrials.gov