Transcranial Magnetic Stimulation in Veterans With PTSD
NCT07336251 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2026-01-21
Summary
With this research investigators hope to begin to understand how rTMS can improve posttraumatic stress disorder (PTSD) symptoms. TMS improves PTSD through two interrelated mechanisms: change in brain limbic system function and change in systemic inflammatory activation. Participants who decide to join this study, will receive ten rTMS treatments. All participants will undergo a 40-minute rTMS procedure with a member of the study team 10 times over 2-4 weeks. Participants will undergo fMRI scans of the head in order to help researchers better understand potential effects of rTMS on brain activity. In addition, participants will be asked to give two breath and blood samples to look for signs of general inflammation.
Conditions
- PTSD - Post Traumatic Stress Disorder
Interventions
- DEVICE
-
Transcranial Magnetic Stimulation
10 sessions of low frequency rTMS (1Hz) applied to the right dorsolateral prefrontal cortex.
Sponsors & Collaborators
-
White River Junction Veterans Affairs Medical Center
lead FED
Principal Investigators
-
Bradley Watts · US Department of Veterans Affairs
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-01-15
- Primary Completion
- 2027-01-31
- Completion
- 2027-01-31
- FDA Device
- Yes
Countries
- United States
Study Locations
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