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PTSD, AUD, and Interpersonal Conflict: Within-person Associations

NCT04552782 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 250

Last updated 2023-05-09

No results posted yet for this study

Summary

The present study seeks to increase understanding of Alcohol Use Disorder (AUD) and Posttraumatic Stress Disorder (PTSD) among veterans, an important public health concern. We will study the effects of regulatory deficits and sleep disturbance on the dynamic course of PTSD and AUD. The study will investigate whether a short, computerized training in the laboratory will alter maladaptive response biases and reduce associations between sleep disturbance, affect and behavioral dysregulation, AUD symptoms, and PTSD symptoms in the real world.

Conditions

  • Stress Disorders, Post-Traumatic
  • Alcoholism

Interventions

BEHAVIORAL

Alcohol CBM

Trains approach or avoidance responses to alcohol cues.

BEHAVIORAL

PTSD CBM

Trains approach or avoidance responses to trauma cues.

BEHAVIORAL

Alcohol Sham

Will not train approach or avoidance responses.

BEHAVIORAL

PTSD Sham

Will not train approach or avoidance responses.

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    collaborator NIH

  • Sioux Falls VA Health Care System

    collaborator FED

  • Bay Pines VA Healthcare System

    collaborator FED

  • University of South Dakota

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-04
Primary Completion
2025-04-30
Completion
2025-04-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04552782 on ClinicalTrials.gov