Mycotoxin Exposure and Dietary Habits in Colorectal Cancer Prevention and Development Among Polish Population

Summary

The aim of the study is the determination of the zearalenone and its metabolites (α and β) level in the blood plasma and faeces of patients at increased risk of cancer, in relation to the nutrition data (FFQ) and information on the quality of life dependent on health (WHOQOL-BREF).

The study is performer within the framework of the Polish Colonoscopy Screening Program. Within the study 100 volunteers between 50 and 65 years of age. while, the colonoscopies will be performed in Provincial Specialist Hospital in Olsztyn. Patients with positive test result, who have been diagnosed with polyps or cancer, will be assigned to risk group. The study has been approved by a local bioethics committee.

Conditions

• Colorectal Cancer, Somatic (Diagnosis)

Interventions

PROCEDURE

colonoscopy

colonoscopy

OTHER

questionnaires

complete the two questionnaires (Food Frequency Questionnaire (FFQ) and the questionnaire of The World Health Organization Quality of Life (WHOQOL-BREF)

OTHER

demographic data collections

completing the demographic questionnaire

OTHER

anthropometric data collections

For the determination of anthropometric data will be used a professional body mass composition analyser (Seca,Hamburg, Germany)

PROCEDURE

Collecte the biological samples

blood and faeces collections

Sponsors & Collaborators

• Provincial Specialist Hospital in Olsztyn

  collaborator UNKNOWN

• Ministry of Health Republic of Poland

  collaborator UNKNOWN

• University of Warmia and Mazury in Olsztyn

  lead OTHER

Principal Investigators

• Tomasz Sawicki, PhD · Department of Human Nutrition, Faculty of Food Science, University of Warmia and Mazury

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

50 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-11-01

Primary Completion

2020-12-31

Completion

2020-12-31

Countries

• Poland

Study Locations