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Possible Association of Intestinal Helminths and Protozoa With Colorectal Cancer Pathogenesis

NCT03173001 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2023-03-03

No results posted yet for this study

Summary

Colorectal cancer (CRC) has the third highest cancer incidence in the world. There is mounting evidence that the intestinal microbiota plays an important role in colorectal carcinogenesis. but there is no information on protozoa of intestinal microbiota except Blastocystis hominis, although data on this issue is scarce. In this study we are going to evaluate the prevalence of intestinal helminthes and protozoa in CRC patients and control group that includes random residents. Patients will be examined before, after surgery and chemotherapy. Parasites and protozoan infection intensity will be estimated by triple coproscopy.

Conditions

  • Colorectal Cancer
  • Colorectal Cancer Metastatic
  • Intestinal Parasite
  • Protozoan Infections

Interventions

DIAGNOSTIC_TEST

Parasitological examination

Three stool samples for parasitological examination will be taken from control subjects and CRC patients at 1-2 days interval.

Sponsors & Collaborators

  • Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-01
Primary Completion
2025-12-31
Completion
2025-12-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03173001 on ClinicalTrials.gov