MedTrace Logo

Administration of Hydrocortisone in Young Healthy Male Volunteers

NCT04137302 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2020-12-07

No results posted yet for this study

Summary

The misuse of cortisone or hydrocortisone for doping purpose in sport has been widely reported in the literature, but to date, no formal testing procedure is available and applicable in an anti-doping laboratory to detect hydrocortisone doping abuse , i.e., administration by systemic way.

The investigators therefore propose to identify biomarkers that clearly distinguish between an authorized local administration of hydrocortisone and a prohibited systemic administration, by studying the impact of 5-day administration of hydrocortisone per 2 different routes.

Conditions

  • Anti-doping Campaign, Detection of Hydrocortisone

Interventions

DRUG

Hydrocortisone administration

Hydrocortisone administration with collection of blood, urine and saliva samples before (1 week), during (5 days) and after (1 week) the 2 treatments

Sponsors & Collaborators

  • French Anti-Doping Agency (AFLD)

    collaborator OTHER_GOV

  • University Hospital, Tours

    collaborator OTHER

  • Centre Hospitalier Régional d'Orléans

    lead OTHER

Principal Investigators

  • AMIOT Virgile, MD · Hospital Regional Center of ORLEANS

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-13
Primary Completion
2020-01-31
Completion
2020-01-31

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04137302 on ClinicalTrials.gov