Systemic Hormones and Muscle Protein Synthesis
NCT03054168 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 34
Last updated 2019-02-26
Summary
This study evaluates the effect of increase in testosterone levels in older males and the effects of decrease in testosterone levels in young males on muscle protein synthesis.
Conditions
- Sarcopenia
- Muscle Hypotrophy
- Muscle Atrophy
Interventions
- DRUG
-
Sustanon 250
The frequency of the injection will be every 2 weeks, 250mg of testosterone, intramuscular injection.
- DRUG
-
Zoladex
The frequency of the injection will be just one injection, 3.6 mg of Zoladex, Subcutaneous injection (abdomen).
- OTHER
-
Placebo
Sponsors & Collaborators
-
University of Nottingham
lead OTHER
Principal Investigators
-
Philip J Atherton, Professor · The University of Nottingham
-
Nathaniel Szewczyk, Ass. Proff · The University of Nottingham
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-12-15
- Primary Completion
- 2018-11-15
- Completion
- 2019-02-15
Countries
- United Kingdom
Study Locations
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