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The Role of Endothelial Dysfunction in Adult Polycystic Kidney Disease

NCT04023214 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2019-07-17

No results posted yet for this study

Summary

This pilot study will compare endothelial function in patients with ADPKD with matched healthy volunteers and normotensive chronic kidney disease stage 1 \& 2 patients. Patients will undergo a single assessment of endothelial function and measurement of plasma and urine levels of biomarkers of endothelial function.

Conditions

  • Polycystic Kidney, Autosomal Dominant

Interventions

DIAGNOSTIC_TEST

Peripheral (digital) arterial tonometry

This will be measured using the EndoPAT system (Itamar Medical)

Sponsors & Collaborators

  • University of Sheffield

    collaborator OTHER

  • Sheffield Teaching Hospitals NHS Foundation Trust

    lead OTHER

Principal Investigators

  • Albert Ong · STH

  • Timothy Chico · STH

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-07-25
Primary Completion
2018-12-31
Completion
2018-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04023214 on ClinicalTrials.gov