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National Unified Renal Translation Research Enterprise - Chronic Kidney Disease

NCT04084145 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 3004

Last updated 2025-04-03

No results posted yet for this study

Summary

Chronic Kidney Disease (CKD) affects around 10% of the adult population and is associated with an increased risk of heart attack, stroke and end stage kidney disease (ESKD). This study aims to better predict who is most likely to progress to ESKD using previously identified risk factors and novel biomarkers in blood and urine samples, along with kidney biopsy tissue. Resources can then be directed to those most at risk of disease progression and other associated conditions such as heart attack and stroke, while those at lower risk can be offered less frequent monitoring.

Conditions

  • Chronic Kidney Diseases

Sponsors & Collaborators

  • Kidney Cancer UK

    collaborator OTHER

  • UK Renal Registry

    collaborator UNKNOWN

  • University of Bristol

    collaborator OTHER

  • University of Birmingham

    collaborator OTHER

  • University of Southampton

    collaborator OTHER

  • University of Geneva, Switzerland

    collaborator OTHER

  • National Institute for Health Research, United Kingdom

    collaborator OTHER_GOV

  • UCB Pharma Ltd

    collaborator UNKNOWN

  • Evotec International GmbH

    collaborator INDUSTRY

  • AbbVie

    collaborator INDUSTRY

  • University of Nottingham

    lead OTHER

Principal Investigators

  • Maarten Taal, MBChB · University of Nottingham

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-07-27
Primary Completion
2032-12-31
Completion
2032-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04084145 on ClinicalTrials.gov