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Fiber Fermentation Kinetics Inside the Gut, and Utilization of Bacterial Metabolites

NCT04013607 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2020-10-14

No results posted yet for this study

Summary

In this study, the life course of SCFA and their regulatory role in human metabolism will be traced using a nose-intestine catheter. The investigators have methodological questions: investigate the envisioned kinetic profiles of stable isotope tracers of SCFAs, and to establish the time points of plasma sampling (to determine systemic availability of SCFAs). The resulting timepoints established in this pilot study will be applied during a future human intervention study.

Conditions

  • Metabolism
  • Dietary Fiber
  • Intestine

Interventions

DIETARY_SUPPLEMENT

fructo- and galacto-oligosaccharides

A NDC drink rich in fructo- and galacto-oligosaccharides

Sponsors & Collaborators

  • University Medical Center Groningen

    collaborator OTHER

  • Wageningen University

    lead OTHER

Principal Investigators

  • Guido Hooiveld, PhD · Wageningen University

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-07-08
Primary Completion
2019-10-17
Completion
2019-10-17

Countries

  • Netherlands

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04013607 on ClinicalTrials.gov