Tolerance and Utilization of Polydextrose, Inulin, and Soluble Corn Fiber
NCT02091349 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2014-05-14
Summary
The objective of this study is to determine the tolerance and utilization of polydextrose and soluble corn fiber through analyses of fecal samples of fermentative end-products (short-chain fatty acids, ammonia, phenol, and indole) and shifts in microbial populations.
Conditions
- Tolerance
Interventions
- OTHER
-
polydextrose
polydextrose- 7, 14, or 21 grams/day 3X3 latin square with 3 periods
- OTHER
-
soluble corn fiber
nutirose- 7, 14, or 21 grams/day
Sponsors & Collaborators
-
University of Illinois at Urbana-Champaign
lead OTHER
Principal Investigators
-
George Fahey, Jr, PhD · UIUC
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 20 Years
- Max Age
- 40 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-07-31
- Primary Completion
- 2011-01-31
- Completion
- 2012-07-31
More Related Trials
-
Trial on Short-chain Fructooligosaccharides, Microbiota, and Constipation in Adults
NCT02140749 ·Status: COMPLETED ·Phase: NA
-
The Inside Study: Oligosaccharides Versus Placebo in Functional Constipation
NCT04282551 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of the Effect of Chicory Inulin-type Fructans in Constipated Adults
NCT05447481 ·Status: COMPLETED ·Phase: NA
-
Evaluating the Synergism of Soluble Dietary Fiber With Fecal Microbiota Transplantation in Slow Transit Constipation
NCT02291354 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Effects of Soluble Dietary Fiber Supplementation
NCT02194972 ·Status: COMPLETED ·Phase: PHASE3
-
Fibers and Gut Health
NCT02234518 ·Status: COMPLETED ·Phase: NA
-
Dose-Responsive Effect of Polydextrose on Whole Gut Transit Time
NCT01540669 ·Status: TERMINATED ·Phase: NA
-
Clinical Study of Resistant Starch in Improving Constipation
NCT06292949 ·Status: RECRUITING ·Phase: NA
-
Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects
NCT05309837 ·Status: COMPLETED ·Phase: NA
-
Pilot Study of the Effect of Fructans on Fermentation in the Colon & Transit
NCT01963364 ·Status: COMPLETED ·Phase: NA
-
Constipation Fiber Trial
NCT02193997 ·Status: COMPLETED ·Phase: NA
-
Fiber Regimens for Constipation Symptoms
NCT03845673 ·Status: COMPLETED ·Phase: NA
-
Effect of TU-100 on Gastrointestinal and Colonic Transit in Humans
NCT00871325 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Efficacy Study of Bowel Preparation Before Colonoscopy
NCT00621920 ·Status: COMPLETED ·Phase: PHASE2
-
Prebiotic Fructans Effect on 1-3 Years Constipated Children's Bowel Habits
NCT03941925 ·Status: UNKNOWN ·Phase: NA
-
Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI
NCT06291272 ·Status: COMPLETED ·Phase: NA
-
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
NCT07202481 ·Status: RECRUITING ·Phase: NA
-
Effect of Consumption of Orafti® Inulin on Bowel Motor Function in Subjects With Constipation
NCT02548247 ·Status: COMPLETED ·Phase: NA
-
Tolerability Study of Panosyl Isomaltooligosaccharides (PIMO), in Subjects With Chronic Idiopathic Constipation (CIC)
NCT05129618 ·Status: COMPLETED ·Phase: NA
-
Dietary Fiber for Fecal Incontinence
NCT01738607 ·Status: COMPLETED ·Phase: NA
-
This Study Aims to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties and Food Effect of IN-114199 in Healthy Participants
NCT06736912 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Effect of a Mixture of Fibers and Carbohydrates on Intestinal Transit in Children Diagnosed With Functional Constipation
NCT04028258 ·Status: UNKNOWN ·Phase: NA
-
Study of NGM282 in Subjects With Functional Constipation and Healthy Individuals
NCT02649062 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Fiber Fermentation Kinetics Inside the Gut, and Utilization of Bacterial Metabolites
NCT04013607 ·Status: COMPLETED ·Phase: NA
-
Effect of TU-100 on Rectal Compliance, Rectal Sensation and Small Bowel and Colonic Transit in Females With Constipation
NCT01139216 ·Status: COMPLETED ·Phase: PHASE1/PHASE2