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Haemodialysis fMRI Salt Appetite Study

NCT04011254 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2023-04-14

No results posted yet for this study

Summary

1. Assessing how the rapid removal of salt and water by haemodialysis alters regional brain activity (by measurement of the brain blood oxygen level-dependent (BOLD) signal using functional MRI) during tasting of soup of differing salt concentrations.
2. Identify differences in the brain response to salt taste pre- and post-haemodialysis between haemodialysis patients who are either able or unable to control between dialysis weight gain

Conditions

  • Dialysis
  • Excess Interdialytic Weight Gain

Interventions

PROCEDURE

haemodialysis

Routine haemodialysis session

Sponsors & Collaborators

  • Yale University

    collaborator OTHER

  • Forschungszentrum Juelich

    collaborator OTHER

  • Imperial College London

    lead OTHER

Principal Investigators

  • Eleanor C Sandhu, MBBS · Imperial College London

  • Tony Goldstone, MRCP PhD · Imperial College London

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-02-17
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04011254 on ClinicalTrials.gov