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Magnesium Sulfate Dose in Obese Patients.

NCT04003688 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 74

Last updated 2021-02-05

No results posted yet for this study

Summary

Magnesium sulfate has been applied in various situations due to actual or potential benefits related to neuroprotection, treatment of eclampsia/pre-eclampsia, arterial hypertension, adrenergic reflex under laryngoscopy/intubation and, shivering, nausea and vomiting, among others. In anesthesia it has been useful as an analgesic adjuvant; however, the method to calculate the dose of magnesium sulfate in obese population is unclear. The objective of this project is to compare two methods of dose calculation based either on the real weight or corrected ideal weight.

Conditions

  • Magnesium Sulfate
  • Postoperative Pain
  • Obesity

Interventions

DRUG

Magnesium sulfate through real weight group

Magnesium sulfate dose 40 mg/kg of actual patient's weight

DRUG

Placebo group

Saline solution (instead of magnesium sulfate, as in the other groups)

DRUG

Magnesium sulfate through ideal corrected weight group

Magnesium sulfate dose 40 mg/kg of ideal corrected patient's weight

Sponsors & Collaborators

  • University of Sao Paulo General Hospital

    lead OTHER

Principal Investigators

  • Joaquim Vieira, Professor · University of Sao Paulo School of Medicine

  • Sebastião Silva Filho, Physician · University of Sao Paulo School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-26
Primary Completion
2020-11-12
Completion
2020-11-12

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04003688 on ClinicalTrials.gov