MedTrace Logo

Adenosine and Magnesium Sulphate as Adjuvants for PECS Block.

NCT03344679 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2017-11-17

No results posted yet for this study

Summary

Pectoral nerve block (PECS) has been used for post-operative pain relief in patients undergoing breast surgery. It has been shown that adenosine has an effect on pain modulation. Magnesium sulphate has been used as an adjuvant to local anaesthetics in many nerve block techniques. We hypothesised that adenosine may affect the PECS block quality. We aimed to compare the effect of adding adenosine to the local anaesthetic and compare its effect to magnesium sulphate when used for PECS block.

Conditions

  • Breast Surgery

Interventions

DRUG

Bupivacaine 0.25%

Bupivacaine 0.25% for PECS block

DRUG

Adenosine 12mg

Adenosine 12 mg for PECS block

DRUG

Magnesium Sulphate 500 mg

Magnesium sulphate 500 mg for PECS block

Sponsors & Collaborators

  • Menoufia University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-02-01
Primary Completion
2017-06-15
Completion
2017-07-22

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03344679 on ClinicalTrials.gov