App-based Versus Slide-based Inter-grader Agreement (IGA) Test for Trachoma Graders

Summary

Trachomatous inflammation-follicular (TF) is diagnosed by looking for clinical signs of infection of everted eyelids (conjunctivae) of children.

The overall objective of this project is to investigate the effectiveness, acceptability and feasibility of an app-based versus slide-based IGA for trachoma graders.

Fieldwork will take place during routine Tropical Data trainings. A non-inferiority randomised controlled trial design will be employed, with grader trainees randomised to app- or slide-based training, and then to app- or slide-based IGA testing. The training and IGA testing method will be compared with field IGA test score to determine which method best predicts passing the field IGA test.

Conditions

• Trachoma

Interventions

OTHER

Inter-grader agreement (IGA) app

A smartphone-based app with images of conjunctivae for trachoma grading training purposes.

Sponsors & Collaborators

• National Institute for Medical Research, Tanzania

  collaborator OTHER_GOV

• Federal Minstry of Health of Ethiopia

  collaborator OTHER_GOV

• Jos University Teaching Hospital

  collaborator OTHER

• University College London Hospitals

  collaborator OTHER

• RTI International

  collaborator OTHER

• Sightsavers

  collaborator UNKNOWN

• World Health Organization

  collaborator OTHER

• Pan American Health Organization

  collaborator OTHER

• London School of Hygiene and Tropical Medicine

  lead OTHER

Principal Investigators

• Emma Harding-Esch · London School of Hygiene and Tropical Medicine

Study Design

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-07-08

Primary Completion

2019-07-12

Completion

2019-07-12

Countries

• Tanzania

Study Locations