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Pneumocystis Jerovici Pneumonia in Infants and Steroids

NCT02149433 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2015-12-11

No results posted yet for this study

Summary

This is a double-blind randomized controlled trial assessing the efficacy of adjuvant corticosteroids in clinically diagnosed Pneumocystis jiroveci pneumonia in infants.

Conditions

  • Pneumonia, Pneumocystis Jerovici

Interventions

DRUG

Prednisone

The steroid regime will be oral prednisone at 2 mg/kg for 7 days, then 1 mg/kg for 7 days, then 0.5mg/kg for 7 days for a total of 21 days.

DRUG

Placebo

Sponsors & Collaborators

  • Kamuzu University of Health Sciences

    lead OTHER

Principal Investigators

  • Laura Newberry, MD · Paediatric Department, College of Medicine, University of Malawi

  • Elizabeth Molyneux, FRCPCH · Paediatric Department, College of Medicine, University of Malawi

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
SINGLE_GROUP

Eligibility

Min Age
2 Months
Max Age
6 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-05-31
Primary Completion
2014-08-31
Completion
2015-02-28

Countries

  • Malawi

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02149433 on ClinicalTrials.gov