Also known as: WHO, World Health Organisation
The WHO approved the first malaria drug for infants weighing under 5kg, and researchers unveiled a single-dose compound, cabamiquine, showing promise in early trials. Investment in the Medicines for Malaria Venture yielded $13 in health benefits per $1 invested, averting 1.6 million deaths.
Real-world studies show nirsevimab reduced RSV infant hospitalizations by up to 72% and maternal vaccination cut hospitalizations by nearly 70%, with benefits extending into the second RSV season.
Clinical trials show a pancreatic cancer drug nearly doubles survival, a head-and-neck therapy shrinks tumors, and new research explains drug resistance. Cancer mortality is falling in the US and UK.
AstraZeneca is expanding in China with a $200m upfront COPD drug license from Sino Biopharmaceutical, a $1.5bn licensing deal for Dizal's Zegfrovy, and a $15bn manufacturing and R&D investment. The deals add revenue-generating assets to its respiratory and oncology portfolios.
A Cochrane review found intermittent fasting did not beat standard diet advice for weight loss. A separate trial found it matched calorie restriction but felt less restrictive. Experts advise a case-by-case approach given limited evidence.
Oncotelic granted Lunai Bioworks worldwide rights to its nose-to-brain delivery system for biodefense and Alzheimer's. Nearly 98% of small-molecule drugs fail to cross the blood-brain barrier.
FDA granted rolling review for Palvella's QTORIN rapamycin NDA. Also covered: global expedited approval pathways, accelerated approval scrutiny, and multi-regional CDx strategies.
The Bundibugyo Ebola outbreak in the DRC has surpassed 3,200 cases and 1,400 deaths, becoming the fastest-spreading Ebola outbreak ever. The first-ever Bundibugyo-specific vaccine trial has begun at Oxford, while healthcare workers at the epicenter have gone on strike over unpaid wages. The WHO has declared the outbreak a global health emergency.
In the Philippines, an estimated 7.3 million adults live with chronic hepatitis B, far above regional averages. Experts warn that complex treatment guidelines may hinder front-line clinicians from initiating care, while Thailand’s success with vaccination shows a path to elimination. Expanding screening and simplifying treatment are critical steps.
The European Medicines Agency is enforcing clinical trial transparency and has launched a new vaccine information initiative, while a coalition of health professionals warns of suboptimal vaccination coverage across Europe. An analysis also shows that only a portion of EMA-approved medicines are available to NHS patients in England after additional assessments.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07432126 |
Community Health Workers Led Integrated Management of Hypertension and Diabetes in Nepal |
RECRUITING | NA |
| NCT07236268 |
Prevalence of HIV and Sexually Transmitted Infections in Migrant Communities in Slovakia |
COMPLETED | |
| NCT07145736 |
Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases |
RECRUITING | PHASE4 |
| NCT07129837 |
Serum Anti-PCOLCE as Novel Diagnostic Biomarker in Rheumatoid Arthritis With Emphasis on Seronegative Patients. |
NOT_YET_RECRUITING | |
| NCT07116447 |
Impact of Alcohol Health Messages in a Real-world Online Retail Setting |
COMPLETED | NA |
| NCT07071792 |
Prevalence of Helmet Associated Neck Pain Among TCS Riders |
COMPLETED | |
| NCT07012876 |
Effectiveness of a Guided Mental Health Chatbot for Youth Living in Lithuania |
ACTIVE_NOT_RECRUITING | NA |
| NCT07008950 |
Self-efficacy and Knowledge (SEEK) Trial to Improve Sexual Reproductive Health and Well-being for Syrian Refugee Women and Girls in Lebanon |
RECRUITING | NA |
| NCT06989398 |
Implementation of the ASCEND Training for Supervisors in Dutch Small and Medium-sized Enterprises (SMEs) |
RECRUITING | NA |
| NCT06979089 |
Implementation of WHO's Doing What Matters in Times of Stress in Dutch Small and Medium-sized Enterprises (SMEs) |
RECRUITING | NA |
