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Identification of the Epigenetic Response to Trauma

NCT03974048 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 365

Last updated 2021-11-09

No results posted yet for this study

Summary

The objective of this study is to investigate potential early alterations in the DNA methylation profile after severe trauma and to investigate if the early marks persist.

Conditions

Interventions

DIAGNOSTIC_TEST

Blood samples for DNA methylation analysis

DNA from blood samples will be isolated and analyzed for genome-wide DNA methylation patterns using the Infinium HumanMethylationEPIC BeadChip (Illumina, San Diego, CA, USA).

Sponsors & Collaborators

  • Rigshospitalet, Denmark

    lead OTHER

Principal Investigators

  • Jacob Steinmetz, MD, Ph.D. · Rigshospitalet, Denmark

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-06-03
Primary Completion
2021-04-15
Completion
2021-08-01

Countries

  • Denmark

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03974048 on ClinicalTrials.gov