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Characterization of the Relationship Between the Human Mesolimbic Reward System and Immune Functioning

NCT03951870 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 85

Last updated 2022-09-22

No results posted yet for this study

Summary

The purpose of this study is to characterize the link between neurobehavioral measures of the mesolimbic reward system and immune functioning in healthy individuals, via fMRI neurofeedback modulation of mesolimbic reward system, and the consecutive assesment of immune response to Hepatitis B vaccination.

Conditions

  • Immune Hepatitis

Interventions

BEHAVIORAL

Neuromodulation via fMRI Neurofeedback task

Two active neurofeedback groups will practice to up regulate their designated neural targets via identical experimental protocol (varying only the origin of the feedback).

BIOLOGICAL

Hepatitis B vaccination

Subjects will be vaccinated against Hepatitis B

Sponsors & Collaborators

  • Technion, Israel Institute of Technology

    collaborator OTHER

  • Tel-Aviv Sourasky Medical Center

    lead OTHER_GOV

Principal Investigators

  • Talma Hendler, MD, PhD · Tel-Aviv Sourasky Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-20
Primary Completion
2022-08-28
Completion
2022-08-28

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03951870 on ClinicalTrials.gov