Modulation of Cortical Brain Activity During Attentional Control
NCT06748976 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 35
Last updated 2025-09-25
Summary
The goal of this study is to determine whether an open-loop sham neurofeedback system can effectively modulate EEG alpha rhythms, which are associated with attentional control. The main questions it aims to answer are:
Does positive sham neurofeedback lead to a decrease in relative EEG alpha power compared to a control condition without feedback?
Researchers will compare the effects of positive and negative sham-neurofeedback conditions to a control condition without feedback to assess the system's impact on alpha rhythm modulation. Participants will:
Experience three conditions (positive sham-neurofeedback, negative sham-neurofeedback, and no feedback) within a virtual reality environment.
Undergo EEG recordings to measure changes in alpha power as a marker of attentional resource allocation.
Provide written informed consent and complete the study following ethical guidelines.
This study seeks to explore the potential of open-loop feedback systems to enhance attentional control by modulating alpha rhythm.
Conditions
- Rumination
- Chronic Pain
- Fibromyalgia
Interventions
- OTHER
-
Positive sham neurofeedback
Participants receive simulated positive reinforcement feedback designed to mimic successful modulation of EEG alpha rhythms, despite the feedback not being directly based on their actual neural activity. This condition aims to create the perception of improved attentional control.
- OTHER
-
Negative sham neurofeedback
Participants receive simulated negative reinforcement feedback that mimics unsuccessful modulation of EEG alpha rhythms, regardless of their actual neural activity. This condition is intended to simulate reduced attentional control.
- OTHER
-
Control
Participants perform the same attentional task but without receiving any feedback. This condition serves as a baseline to evaluate the effects of the sham neurofeedback interventions on EEG alpha rhythm modulation.
Sponsors & Collaborators
-
National Council of Scientific and Technical Research, Argentina
lead OTHER_GOV
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-07-01
- Primary Completion
- 2025-11-30
- Completion
- 2025-11-30
Countries
- Argentina
Study Locations
More Related Trials
-
Brain Activity Changes Measured by EEG and fMRI on Healthy Volunteers After Complex Somatosensory Stimulation
NCT01079689 ·Status: COMPLETED ·Phase: NA
-
Study on Neurofeedback and Relaxation
NCT04545359 ·Status: UNKNOWN ·Phase: NA
-
Neurofeedback in Patients With Frontal Brain Lesions
NCT02957695 ·Status: COMPLETED ·Phase: NA
-
Increasing Sensori-Motor Rhythm Activity by EEG-Neurofeedback to Reduce the Impact of Pain on Daily Functioning
NCT06234917 ·Status: COMPLETED ·Phase: NA
-
Investigating Electroencephalographic Predictors of Default Mode Network Anticorrelation in Healthy Adults
NCT05592600 ·Status: COMPLETED ·Phase: NA
-
Development of MRI Protocols and Associated Explorations (EEG, NIRS) in Voluntary Patients
NCT03160235 ·Status: COMPLETED ·Phase: NA
-
A Meditation Intervention on Subconcussive Head Impacts
NCT04225663 ·Status: COMPLETED ·Phase: NA
-
Brain Rhythms in Fibromyalgia: A Magnetoencephalography (MEG) Study
NCT02159300 ·Status: COMPLETED
-
Physiology of Interregional Connectivity in the Human Brain
NCT03723434 ·Status: UNKNOWN ·Phase: NA
-
Neurofeedback Impact on Veterans With mTBI
NCT04195685 ·Status: COMPLETED ·Phase: NA
-
Modulation of Brain Oscillations Underlying Working Memory
NCT05923606 ·Status: RECRUITING ·Phase: NA
-
Metabolic Activation of Brain Areas With Emotional Stimuli Compared With Score in Psychological Test
NCT04974437 ·Status: COMPLETED
-
Neural Mechanisms for Reducing Interference During Episodic Memory Formation
NCT05092100 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Interactions Between Attentional Networks and Their Influence on Perception
NCT02467114 ·Status: COMPLETED ·Phase: NA
-
Scrutinizing and Promoting Mindfulness Via New Technologies
NCT03148678 ·Status: COMPLETED ·Phase: NA
-
Targeting Large-scale Networks in Depression With Real-time fMRI (Functional Magnetic Resonance Imaging) Neurofeedback
NCT05934604 ·Status: COMPLETED ·Phase: NA
-
Study Pilot - Hybrid EEG/fMRI Neurofeedback in Depressed Patients
NCT04450186 ·Status: UNKNOWN ·Phase: NA
-
QSPainRelief-patientCNS : Clinical Biomarkers of Nociception, Sedation and Cognition
NCT04742790 ·Status: UNKNOWN ·Phase: NA
-
Efficacy and Mechanism of Acupuncture for Chronic Sciatica Using fMRI
NCT03350789 ·Status: UNKNOWN ·Phase: NA
-
Study of Brain Anatomo-functional Substrates Related to the Use of Human Tool by Means of Simultaneous Acquisition of Magnetic Resonance Imaging and Electroencephalogram
NCT05767489 ·Status: UNKNOWN
-
Investigating the Effect of Normal Frequency-band and Infra-low Frequency Neurofeedback on Functional Brain Connectome
NCT05711550 ·Status: COMPLETED ·Phase: NA
-
An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect
NCT01079390 ·Status: COMPLETED ·Phase: NA
-
Symptom Based Treatment Affects Brain Plasticity - the Role of Verbal Auditory Hallucinations
NCT02722915 ·Status: COMPLETED ·Phase: NA
-
Fronto-limbic Functional Connectivity Via Real-time fMRI Neurofeedback
NCT02692196 ·Status: COMPLETED ·Phase: NA
-
Descriptive Pilot Study of the Effects of a Standardized Neuromodulation Program on Cortical Brain Function in Chronic Low Back Pain Patients
NCT03929952 ·Status: COMPLETED ·Phase: NA