MedTrace Logo

Abdominal Regional Perfusion in Donation After Cardiac Death for Multi-Organ Transplantation

NCT03946852 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2019-05-13

No results posted yet for this study

Summary

The main purpose of this study is to increase the pool of organs available for donation by performing ARP to recondition donation after cardiac death (DCD) organs prior to transplantation. We will compare the outcomes of our ARP DCD liver transplants with historical data to determine the efficacy of this treatment compared to transplantation with standard DCD and donation after brain death (DBD) organs. We will also analyze biological samples from donors and recipients and compare them with outcome data in an effort to determine if any biological markers are able to predict the quality/success of the grafts.

Conditions

  • Liver Transplant; Complications
  • Ischemia Reperfusion Injury
  • Cirrhosis
  • Liver Cancer
  • Liver Metastases
  • End Stage Liver Disease

Interventions

DEVICE

Abdominal Regional Perfusion

Abdominal Regional Perfusion

Sponsors & Collaborators

  • London Health Sciences Centre

    lead OTHER

Principal Investigators

  • Ephraim S Tang, MD, MSc · Clinical Fellow

  • Anton I Skaro, MD, PhD · Transplant Surgeon

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-06-30
Primary Completion
2021-06-30
Completion
2026-06-30

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03946852 on ClinicalTrials.gov