MedTrace Logo

Remote Ischaemic Preconditioning in Transplantation (RIPTRANS)

NCT03855722 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 496

Last updated 2020-03-10

No results posted yet for this study

Summary

Remote ischemic preconditioning (RIPC) is a concept where remotely induced ischemia produces protection against ischemia-reperfusion injury in a remote organ. RIPC has been studied extensively in animal models and heart surgery, but it's benefit in transplantation has been studied less. The primary aim of this study is to find out whether RIPC performed in a donor in donation after brain-death (DBD) could improve delayed graft function rate of kidney transplants.

Conditions

  • Transplant Dysfunction

Interventions

PROCEDURE

RIPC

Remote Ischaemic Preconditioning

PROCEDURE

Sham-RIPC

Sham procedure

Sponsors & Collaborators

  • Finska Läkaresällskapet (funding)

    collaborator UNKNOWN

  • Academy of Finland

    collaborator OTHER

  • Helsinki University Hospital Research Funds (funding)

    collaborator UNKNOWN

  • Helsinki University Central Hospital

    lead OTHER

Principal Investigators

  • Aki Uutela, MD · Helsinki University Central Hospital

  • Ville Sallinen, MD, PhD · Helsinki University Central Hospital

  • Marko Lempinen, MD, PhD · Helsinki University Central Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-12
Primary Completion
2022-03-31
Completion
2042-02-28

Countries

  • Finland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03855722 on ClinicalTrials.gov