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Evaluation of the Efficacy and Tolerability of Autologous Adipose Tissue Derived Stem Cells on Facial Rejuvenation

NCT03928444 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2019-09-30

No results posted yet for this study

Summary

This study is to evaluate the efficacy and tolerability of autologous adipose tissue derived stem cells in facial rejuvenation.

Conditions

  • Skin Rejuvenation

Interventions

PROCEDURE

intradermal injection of adipose derived stem cells to one side of the face

Lipoaspiration for preparation of ADSC will be done according to the following technique: Under local anesthesia using strict aseptic technique, a small incision will be done in the lateral aspect of the thigh or lower abdomen, through which the infiltration cannula will be introduced to inject the local anesthetic solution using the wet technique. This will be followed 15 minutes later by lipo-aspiration of (50 ml fat ) using a blunt tipped cannula under the negative suction pressure of a 60 ml syringe. * Autologous adipose tissue derived stem cells (At-ADSCs) will be separated from the lipo-aspirate using enzymatic digestion and differential centrifugation in the Center of Excellence for Research in Regenerative Medicine and its Application (CERRMA), Alexandria Faculty of Medicine. * Viability of collected cells will be checked using trypan blue stain. Characterization of the isolated ADSCs population will be performed by flow cytometry.

PROCEDURE

intradermal injection of saline to one side of the face

intradermal injection of saline to one side of the face

Sponsors & Collaborators

  • Alexandria University

    lead OTHER

Principal Investigators

  • Carmen Ibrahim Farid Mohammed Amin, MD · Assistant Professor of Dermatology, Faculty of Medicine, Alexandria University

  • Ossama Hussein Roshdy, MD · Professor of Dermatology, Faculty of Medicine, Alexandria University

  • Wafaa Ibrahim Abdullah, MD · Professor of Dermatology, Faculty of Medicine, Alexandria University

  • Radwa Ali Mehanna, PhD · Assistant Professor of Physiology, Faculty of Medicine, Alexandria University

  • Nader Hussein Lotfy Bayoumi., MD, FRCS · Professor of ophthalmology , Faculty of Medicine, Alexandria University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
35 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-01
Primary Completion
2019-08-06
Completion
2019-08-06

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03928444 on ClinicalTrials.gov