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Autologous Facial Fat Grafting Study

NCT05482425 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26

Last updated 2025-11-05

No results posted yet for this study

Summary

The goal of this study is to specifically examine changes in facial skin appearance after facial fat grafting with autologous fat tissue that has either been washed with sterile saline before injecting, or left unwashed. This will be testing two variations of a standard of care surgical procedure, in two cohorts of subjects. One group will receive washed fat, and one group will receive unwashed fat, to both sides of the face. There are no experimental devices, drugs, or biological agents being used in this study. All fat tissue is autologous from the subjects treated.

Significance: This study will provide evidence that may directly impact clinical practice for a common procedure in plastic surgery. Regardless of whether the null hypotheses is accepted or rejected, the data will be of direct clinical use and impact practice in the operating room.

Conditions

  • Facial Skin Texture
  • Facial Skin Pigmentation

Interventions

OTHER

Autologous facial fat graft injection

Participants will received either a washed or unwashed autologous facial fat graft injection to both sides of the face, as determined by randomization.

Sponsors & Collaborators

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • J. Peter Rubin, MD · University of Pittsburgh

  • Patsy Simon, BS, RN, CCRC, CCRA, ACRP-PM · University of Pittsburgh

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-17
Primary Completion
2025-09-30
Completion
2025-09-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05482425 on ClinicalTrials.gov