mRNA and miRNA Airway Inflammatory Markers
NCT03924843 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 21
Last updated 2021-07-09
Summary
This study investigates cytokine Messenger (mRNA) and microRNA (miRNA) level expression of interleukin (IL) -6, IL-8, IL-17, tumor necrosis factor (TNF)-alpha, monocyte chemoattractant protein (MCP)-1, macrophage inflammatory protein (MIP)-1 beta and transforming growth factor (TGF)-beta regarding their reproducibility and responsivity in induced sputum and nasal mucosa of patients with chronic obstructive pulmonary disease (COPD) in order to assess their potential as a biomarker outcome measure.
Conditions
- COPD
- COPD Exacerbation
Sponsors & Collaborators
-
University Medical Center Groningen
lead OTHER
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-11-14
- Primary Completion
- 2021-02-27
- Completion
- 2021-03-30
Countries
- Netherlands
Study Locations
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