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Dental Hygiene and Peri-Implant Tissues Homeostasis Ancillary Study

NCT03917264 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2023-07-05

No results posted yet for this study

Summary

Peri-implantitis is an inflammatory disease that leads to loss of jawbone around dental implants. Recent discoveries have identified increased release of Titanium (Ti) particles around implants as being associated to peri-implantitis. In this ancillary study to the Dental Hygiene and Peri-Implant Tissues Homeostasis trial the objective is to determine potential triggers of increased Ti dissolution from the implant surface and the mechanisms by which Ti dissolution products amplify peri-implant inflammation. Results from this study will determine whether there is a differential response to Ti particles across individuals, which may alter susceptibility to peri-implantitis.

Conditions

  • Peri-Implantitis

Interventions

PROCEDURE

Peri-implantitis debridement

Mechanical cleaning of titanium implants, peri-implantitis debridement.

OTHER

Dental hygiene procedures

Titanium scalers and nylon brushed used for implant cleaning

Sponsors & Collaborators

Principal Investigators

  • Georgios Kotsakis, DDS, MS · UTHealth San Antonio

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
25 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-11-22
Primary Completion
2023-06-01
Completion
2023-06-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03917264 on ClinicalTrials.gov