MedTrace Logo

Evaluation of Implantoplasty in the Treatment of Peri-Implantitis.

NCT06884475 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-03-17

No results posted yet for this study

Summary

The aim of this longitudinal study is to evaluate the clinical impact of implantoplasty in the treatment of peri-implantitis, exploring the potential effect of removing compromised implants on periodontal health and its correlation with the presence of titanium particles in the crevicular fluid. In addition, we seek to investigate changes in the peri-implant microbiological profile before and after implantoplasty, allowing a more comprehensive understanding of the effects of this procedure at both the biological and clinical levels, considering microbiological factors and the relationship with titanium, inflammation and peri-implant health. Forty participants diagnosed with peri-implantitis will be selected (n = 20 in each group) to participate in the study. They will be randomly allocated into two groups, according to the treatment to be performed (implantoplasty group and surgical access group for scaling). Using a millimeter-diameter periodontal probe, the initial clinical parameters of patients with periodontal and peri-implant disease will be evaluated. Biofilm and crevicular fluid will then be collected using sterile paper cones from one implant of each patient in all groups at follow-up intervals of 1, 3 and 6 months for subsequent processing and evaluation of the data. The integration of these analyses aims to offer valuable insights to optimize peri-implantitis treatment strategies, aiming at the health and longevity of dental implants.

Conditions

  • Peri-Implantitis and Peri-implant Mucositis

Interventions

PROCEDURE

Implantoplasty

Following clinical and radiographic examinations and thorough case planning, surgical procedures were performed under local anesthesia by a operator. After, anesthesia, surgical access will be performed for debridement and implantoplasty of the affected dental implant.

PROCEDURE

Surgical access

Following clinical and radiographic examinations and thorough case planning, surgical procedures were performed under local anesthesia by a operator. After, anesthesia, only surgical access will be performed for debridement without implantoplasty of the affected dental implant.

Sponsors & Collaborators

  • University of Campinas, Brazil

    lead OTHER

Principal Investigators

  • Renato Casarin, PhD · University of Campinas, Brazil

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-01
Primary Completion
2026-04-01
Completion
2026-07-01

Countries

  • Brazil

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06884475 on ClinicalTrials.gov