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IMRT With Carboplatin Versus IMRT With Carboplatin and Fluorouracil for Eldly Esophageal Cancer Patients

NCT03910634 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 264

Last updated 2019-04-10

No results posted yet for this study

Summary

An open, single-center, randomized controlled phase II clinical trial to compare the efficacy and safety of conformal intensity modulated radiation therapy (IMRT) combined with carboplatin and IMRT combined with carboplatin and 5-FU in elderly patients with locally advanced esophageal squamous cell carcinoma at high risk of chemotherapy

Conditions

  • Esophageal Cancer
  • Radiotherapy Side Effect

Interventions

DRUG

Fluorouracil

1.33g/body surface QW1, continuous intravenous infusion for 72 hours, repeated for 4 weeks

RADIATION

Intensity modulated radiation therapy

Radiotherapy for 5-6 weeks，50-60Gy

DRUG

carboplatin

Carboplatin (AUC 2), QW1, intravenous drip, repeat for 4 weeks

Sponsors & Collaborators

  • Sun Yat-sen University

    lead OTHER

Principal Investigators

  • Yonghong Hu, Doctor · Sun Yat-sen University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-04-09
Primary Completion
2020-12-31
Completion
2021-12-31

Countries

  • China

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03910634 on ClinicalTrials.gov