A Trial Estimating The Optimal Radiation Volume Of Postsurgical Radiation For Patients With Esophageal Cancer

Summary

A randomized phase II trial to estimate the optimal radiation volume of postsurgical radiation for patients with locoregionally advanced thoracic esophageal squamous cell carcinoma (T3-4, any N, M0).

Conditions

• Esophageal Squamous Cell Carcinoma

Interventions

RADIATION

enlarge irradiation volume

In Arm A, postsurgical radiation target volume includes tumor bed and elective nodes area

RADIATION

Small volume radiation

In Arm B, postsurgical radiation target volume includes tumor bed only

DRUG

cisplatin

DRUG

fluorouracil

Sponsors & Collaborators

• The First Affiliated Hospital of Soochow University

  collaborator OTHER

• The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China

  collaborator OTHER

• Jiangsu Cancer Institute & Hospital

  collaborator OTHER

• Affiliated Hospital of Jiangsu University

  collaborator OTHER

• Zhejiang Cancer Hospital

  collaborator OTHER

• First Affiliated Hospital of Wenzhou Medical University

  collaborator OTHER

• Zhejiang University

  collaborator OTHER

• The First Affiliated Hospital of Anhui Medical University

  collaborator OTHER

• Anhui Provincial Hospital

  collaborator OTHER_GOV

• Fujian Cancer Hospital

  collaborator OTHER_GOV

• Shanghai Chest Hospital

  collaborator OTHER

• Shanghai Pulmonary Hospital, Shanghai, China

  collaborator OTHER

• RenJi Hospital

  collaborator OTHER

• Fudan University

  lead OTHER

Principal Investigators

• Xiao-Long Fu, M.D, Ph.D. · Fudan University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-04-30

Primary Completion

2013-12-31

Countries

• China

Study Locations