Synchronous or Sequential Radiotherapy for Advanced Esophageal Squamous Cell Carcinoma With Oligometastases.
NCT06143722 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 63
Last updated 2023-11-22
Summary
A randomized, prospective phase II trial was conducted to explore the timing of radiotherapy intervention in combination with chemotherapy and immunotherap in order to provide an effective treatment for patients with advanced esophageal squamous carcinoma with oligometastases.
Conditions
- Advanced Esophageal Squamous Carcinoma With Oligometastases
Interventions
- RADIATION
-
simultaneous with radiotherapy
Chemotherapy combined with immunotherapy simultaneous with radiotherapy
- RADIATION
-
synchronous with radiotherapy
Chemotherapy combined with immunotherapy synchronous with radiotherapy
Sponsors & Collaborators
-
West China Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-11-30
- Primary Completion
- 2025-11-30
- Completion
- 2026-11-30
More Related Trials
-
Camrelizumab Combined With Neoadjuvant Concurrent Chemoradiotherapy for Resectable Locally Advanced ESCC(NICE-RT)
NCT05650216 ·Status: UNKNOWN ·Phase: PHASE2
-
Immunotherapy Plus Chemotherapy vs. Chemoradiotherapy for Thoracic Squamous Esophageal Carcinoma
NCT05821452 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Camrelizumab in Combination With Apatinib Mesylate Plus Short-course Chemotherapy for Advanced ESCC
NCT05738434 ·Status: RECRUITING ·Phase: PHASE2
-
Camrelizumab in Combination With Radiotherapy for Neoadjuvant Esophageal Carcinoma.
NCT05176002 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Camrelizumab in Combination With Neoadjuvant Chemotherapy for Resectable Thoracic Esophageal Squamous Cell Carcinoma
NCT04506138 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Neoadjuvant Therapy of Camrelizumab Combined With Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma
NCT05476380 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Simultaneous Modulated Accelerated Radiation Therapy Concurrent With Chemotherapy to Treat Esophageal Cancer
NCT01670409 ·Status: COMPLETED ·Phase: PHASE2
-
Hypofractionated vs. Conventional Chemoradiotherapy After Induction Chemo-immunotherapy for Unresectable Esophageal Squamous Cell Carcinoma
NCT06912074 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Camrelizumab As Consolidation Therapy After Radical Concurrent Chemoradiotherapy In Locally Advanced ESCC
NCT04286958 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Radiochemotherapy Combined With Cadonilizumab for Local Advanced Esophageal Squamous Cell Cancer
NCT07016724 ·Status: RECRUITING ·Phase: PHASE2
-
A Multicenter, Randomized Controlled, Phase II Clinical Study of First-line Chemotherapy and Camrelizumab With or Without Radiotherapy in the Treatment of Oligometastatic Esophageal Cancer
NCT05183958 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Patients With Locoregionally Advanced Esophageal Squamous Cell Carcinoma
NCT03600831 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study of Perioperative Camrelizumab Combined With Chemotherapy in Patients With Resectable ESCC
NCT05182944 ·Status: RECRUITING ·Phase: PHASE2
-
Simultaneous Modulated Accelerated Boost Versus Standard Dose Radiotherapy in Esophageal Cancer
NCT02556762 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Neoadjuvant Chemotherapy With Camrelizumab in Locally Advanced Esophageal Squamous Cell
NCT04520035 ·Status: UNKNOWN ·Phase: PHASE2
-
S-1 IMRT Versus S-1 and Cisplatin Concurrent IMRT in Inoperable Esophageal Squamous Cell Carcinoma
NCT02913066 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Camrelizumab Combined With Chemotherapy as Neoadjuvant Therapy in Adcanced Esophageal Squamous Cell Carcinoma (ESCC)
NCT04767295 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase Ⅱ Clinical Trial of Camrelizumab for Adjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma
NCT04533490 ·Status: UNKNOWN ·Phase: PHASE2
-
IMRT With Carboplatin Versus IMRT With Carboplatin and Fluorouracil for Eldly Esophageal Cancer Patients
NCT03910634 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase II Study of Different Doses of Radiotherapy Combined With Sintilimab in the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma
NCT06468644 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Carrelizumab Combined With Chemotherapy for Adjuvant Therapy of Esophageal Squamous Cell Carcinoma
NCT05637268 ·Status: UNKNOWN ·Phase: PHASE2
-
A Real-world Study Evaluating the Usage of Camrelizumab in Chinese Patients With Advanced Esophageal Cancer
NCT04616040 ·Status: NOT_YET_RECRUITING
-
Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma in the Era of Immunotherapy
NCT06272214 ·Status: RECRUITING ·Phase: PHASE2
-
Simultaneous Integrated Boost Radiotherapy and Concurrent Chemotherapy for Locally Advanced Esophageal Carcinoma
NCT02429622 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Comparable Study of Different Radiation Dose in Esophageal Carcinoma
NCT01937208 ·Status: UNKNOWN ·Phase: PHASE3